An NIMH-supported study of the 3D genome revealed widespread silencing of genes with important roles in brain function in fragile X syndrome and related disorders.
Source: nimh
The BRAIN Initiative® Cell Atlas Workshop: From Single-Cell Genomics to Brain Function and Disorders—Data Integration and Annotation
This workshop will be a 3-day interactive event with targeted and coordinated presentations, panel discussions, and demonstrations with the following goals: 1. Foster the development of data standards for the integration and annotation of single-cell genomics data. 2. Systemize and automate the process of data to information to knowledge and develop pipelines where feasible. 3. Shed new insights on brain cell functional studies by using cell atlasing data and cell type-specific targeting tools. 4. Develop strategies with brain disease research communities to maximally leverage BICCN / BICAN data. 5. Develop a community roadmap for the analysis and annotation of single cell data.
Source: nimh
NIMH Hosts 75th Anniversary Symposium
The National Institute of Mental Health recently hosted a symposium to kick off its 75th Anniversary celebrations.
Source: nimh
Reddit “Ask Me Anything” with NIMH Director, Dr. Joshua A. Gordon and Deputy Director, Dr. Shelli Avenevoli
NIMH's Director and Deputy Director will answer questions about NIMH’s research priorities, progress made, and challenges ahead in the coming years.
Source: nimh
Using Games to Explore the Mind
The National Institute of Mental Health (NIMH) and the non-profit organization The Many Brains Project partnered with the National Institutes of Health (NIH) All of Us Research Program to adapt a series of new game-like tasks that are now part of the All of Us Research Program’s participant experience.
Source: nimh
Sex as a Biological Variable (SABV) Policy for Studies Using Non-Human Primates in Neuroscience Research
This day-long virtual workshop will give the neuroscience community an opportunity to discuss how the NIH Policy on Sex as a Biological Variable is applied to studies using non-human primates.
Source: nimh
Disparities in Psychotic Disorder Diagnoses and Other Negative Health Outcomes
NIMH researchers found racial and ethnic disparities in rates of psychotic disorders, which were associated with co-occurring medical conditions and negative health outcomes.
Source: nimh
Magnetic Seizure Therapy as Effective as Electroconvulsive Therapy for Treating Depression
This clinical trial found that MST is equally effective at reducing depression symptoms as ECT, but with fewer side effects.
Source: nimh
Alaina Tillman, Winner of the 2023 NIMH Three-Minutes Talks Competition
Alaina Tillman discusses psychiatry is moving toward a precision medicine model. For patients diagnosed with depression, selective serotonin re-uptake inhibitors, SSRIs, are the most common treatment administered. However, for SSRIs, only about half of patients experience a relief of symptoms.
Source: nimh
Annie Ilsley, Winner of the 2023 NIMH Three-Minute Talks Competition
Annie Ilsley discusses white matter composes about half the brain and forms pathways that are essential for communication between regions. Myelination is a key, neurodevelopmental process in which a fatty sheath, known as myelin, envelops neuronal axons that form white matter tracks, acting as insulation and allowing for efficient conduction through these pathways.
Source: nimh
