The goal of this concept is to generate comprehensive evidence to determine whether immunotherapeutic strategies, including broadly neutralizing antibodies (bNAbs) and antibody-derived constructs, can safely and effectively target HIV persistence within the central nervous system (CNS) compartment while mitigating neuroimmune dysfunction and improving mental health outcomes.
Source: nimh

The goal of this concept is to reissue and extend the NIMH Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers program. The ALACRITY Centers program is intended to support high-impact, practice-based research with near-term potential to significantly advance clinical practice and generate knowledge that will fuel transformation of mental health care in the United States.
Source: nimh

This is a reissue of the informatics infrastructure program announcement for The Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative data ecosystem. This program has established domain-specific archives that serve as primary repositories for scientific data generated across the BRAIN research portfolio, providing long-term maintenance, standardized curation, compliance with NIH data management and sharing policy, and broad community access. This concept calls for continued support for the data archive component of that infrastructure.
Source: nimh

The goal of this concept is to continue supporting an integrated BRAIN® Initiative Cell Atlas Network (BICAN) Coordinating Unit for Biostatistics, Informatics, and Engagement (CUBIE) that will (i) enable the exploration of large-scale brain cell atlas data and knowledge, (ii) inspire research in brain function and disorders, and (iii) ensure research rigor and data reproducibility by making the data Findable, Accessible, Interoperable, and Reusable (FAIR). This will provide the foundation for a knowledge base with consensus brain cell taxonomies, ontologies, and community data standards.
Source: nimh

This is a re-issue of a long-standing R25 program announcement that aims to support educational activities that complement and/or enhance the training of a workforce to meet the nation’s biomedical, behavioral and clinical research needs. To address this goal, this concept would focus specifically on mentoring activities and in particular, mentoring networks.
Source: nimh

This is a re-issue of a long-standing R25 program announcement that aims to support educational activities that complement and/or enhance the training of a workforce to meet the nation’s biomedical, behavioral and clinical research needs. To address this goal, this concept would focus specifically on mentoring activities and in particular, mentoring networks.
Source: nimh

The purpose of the Conte Centers program is to support interdisciplinary teams of researchers engaged in novel, creative, and integrated experimental approaches to address high-risk, high-impact scientific questions in either basic neuroscience research or in translational research that will significantly advance the state of the science in brain and behavioral research and provide the foundation for understanding mental disorders and/or transform the understanding and treatment of mental illnesses.
Source: nimh

This is a re-issue of a long-standing R25 program announcement. The overarching goals of this initiative are to: (1) complement and/or enhance the training of a workforce to meet the nation’s biomedical, behavioral, and clinical research needs; (2) help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral, and clinical sciences; and (3) foster a better understanding of biomedical, behavioral, and clinical research and its implications.
Source: nimh

This effort aims to stimulate research in a major gap area in pediatric psychopharmacology for psychiatric and neurodevelopmental disorders, by encouraging the development of objective pediatric central nervous system (CNS) measures that can be incorporated into pharmacologic trials.
Source: nimh

The goal of this concept is to support the extension of the Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ) Data Processing, Analysis and Coordination Center to complete final data processing and analysis required to complete the study.
Source: nimh