Scientists have deciphered the molecular structure of a widely-prescribed antipsychotic docked in its key human brain receptor. The discovery may hold clues to designing better treatments for schizophrenia, bipolar disorder and other mental illnesses.
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NIMH leadership has defined a set of principles to help compare the quality of research proposals across the full breadth of the Institute’s portfolio; Dr. Gordon explains how these principles can help ensure that NIMH prioritizes excellent science while assuring portfolio balance across timeframes.
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The primary goal of this initiative is to encourage research that would develop and validate new screening methods for autism spectrum disorders (ASD) that can be used in infancy (0-12 months of age).
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The goals of this concept are to encourage research to test the feasibility and effectiveness of a stepped-care intervention model; to improve symptoms and functioning for individuals at “clinical high risk” (CHR) for psychosis; and to reduce rates of transition to a psychotic disorder.
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A gene crucial for learning can send its genetic material from one neuron to another by employing a strategy commonly used by viruses.
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NIMH researchers have developed a brief screening questionnaire for medical professionals to identify youth at risk for suicide.
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The NIMH Research Domain Criteria (RDoC) unit holds monthly virtual “office hours” via video conference. Discussion topics may include the basic principles of the initiative, general queries about designing and applying for grants based on RDoC ideas, and the role of RDoC within NIMH and its relationship to other initiatives. Questions regarding individual grant applications or detailed program advice will be redirected to the relevant program officers.
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Research in a wide range of disciplines supports the idea that mental disorders result from the complex interplay of biological, developmental, social, and environmental processes; however, the more we learn about mental disorders, the more we realize there are still gaps in our understanding of how best to classify, diagnose, and treat them.
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National Institute of Mental Health Alliance for Research Progress September 2017 Meeting Summary, Agenda, and Participant List
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Join experts for this live videocast about adolescent suicide prevention, which will include techniques for early detection and management of young people at risk.
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